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Recombinant IL-9 anticorps

Cet anticorps anti-IL-9 est un anticorps Lapin Chimeric détectant IL-9 dans FACS et BP. Adapté pour Souris.
N° du produit ABIN7072551

Aperçu rapide pour Recombinant IL-9 anticorps (ABIN7072551)

Antigène

Voir toutes IL-9 (IL9) Anticorps
IL-9 (IL9) (Interleukin 9 (IL9))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 43
  • 41
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
Souris

Hôte

  • 55
  • 18
  • 9
  • 3
  • 2
  • 2
Lapin

Clonalité

  • 53
  • 34
  • 2
Chimeric

Conjugué

  • 54
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IL-9 est non-conjugé

Application

  • 59
  • 31
  • 24
  • 23
  • 14
  • 13
  • 13
  • 12
  • 7
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Blocking Peptide (BP)

Clone

D9302C12
  • Fonction

    Anti-IL-9 [D9302C12], Rabbit IgG, kappa

    Specificité

    This antibody is specific for murine IL-9.

    Attributs du produit

    Original Species of Ab: Hamster, Armenian

    Original Format of Ab: IgG

    Purification

    Protein A affinity purified

    Immunogène

    This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.

    Isotype

    IgG kappa
  • Indications d'application

    In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    IL-9 (IL9) (Interleukin 9 (IL9))

    Autre désignation

    IL-9

    Sujet

    Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40

    UniProt

    P15247

    Pathways

    Signalistation JAK/STAT
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